| Assay ID | Title | Year | Journal | Article |
|---|
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1232251 | Antagonist activity against mu opioid receptor (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1139353 | Binding affinity to muscarinic M1 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139356 | Binding affinity to muscarinic M4 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139352 | Binding affinity to histamine H1 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1232253 | Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS binding assay | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1139357 | Binding affinity to NET (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139350 | Inhibition of delta opioid receptor (unknown origin) using SNC-80 by high content imaging beta-arrestin translocation assay | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139363 | Drug metabolism in human liver microsomes assessed as compound remaining after 1 hr | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1232257 | Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69,593 stimulation for 90 mins by DiscoveRx beta-arrestin2 recruitment based PathHunter assay relative to co | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1139348 | Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by DiscoveryRx b-arrestin PathHunter assay | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139349 | Inhibition of kappa opioid receptor (unknown origin) using dynorphin A by high content imaging beta-arrestin translocation assay | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139354 | Binding affinity to muscarinic M2 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1232260 | Binding affinity to mu opioid receptor (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1232259 | Binding affinity to delta opioid receptor (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1232254 | Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK phosphorylation pre-incubated with compound before U69,593 stimulation for 10 mins | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1139383 | Binding affinity to adrenergic alpha2C receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1232256 | Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK phosphorylation pre-incubated with compound before U69,593 stimulation for 10 mins relative to control | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1232252 | Antagonist activity against delta opioid receptor (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1232255 | Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69,593 stimulation for 90 mins by DiscoveRx beta-arrestin2 recruitment based PathHunter assay | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1139358 | Binding affinity to sigma-1 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1232258 | Displacement of radio-labeled U69,593 from rat kappa opioid receptor expressed in HEK293 cell membranes | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| AID1139347 | Inhibition of mu opioid receptor (unknown origin) using DAMGO by high content imaging beta-arrestin translocation assay | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139355 | Binding affinity to muscarinic M3 receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1139351 | Binding affinity to 5-HT2B receptor (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, May-01, Volume: 24, Issue:9
| Antagonists of the kappa opioid receptor. |
| AID1232250 | Antagonist activity against human kappa opioid receptor by DiscoveRx beta-arrestin2 recruitment based PathHunter assay | 2015 | Bioorganic & medicinal chemistry, Jul-15, Volume: 23, Issue:14
| Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |